Michael Mahler Selected Research

Anti-Citrullinated Protein Antibodies

4/2024	Utility of testing for third-generation anticyclic citrullinated peptide (anti-CCP3) antibodies in individuals who present with new musculoskeletal symptoms but have a negative second-generation anticyclic citrullinated peptide (anti-CCP2) antibody test.
1/2022	Ultrasound subclinical synovitis in anti-CCP-positive at-risk individuals with musculoskeletal symptoms: an important and predictable stage in the rheumatoid arthritis continuum.
10/2021	Combinations of Anticyclic Citrullinated Protein Antibody, Rheumatoid Factor, and Serum Calprotectin Positivity Are Associated With the Diagnosis of Rheumatoid Arthritis Within 3 Years.
11/2020	Third-Generation Anti-Cyclic Citrullinated Peptide Antibodies Improve Prediction of Clinical Arthritis in Individuals at Risk of Rheumatoid Arthritis.
12/2019	Anticyclic Citrullinated Peptide Antibodies 3.1 and Anti-CCP-IgA Are Associated with Increasing Age in Individuals Without Rheumatoid Arthritis.
7/2017	Anti-citrullinated protein antibodies in the diagnosis of rheumatoid arthritis (RA): diagnostic performance of automated anti-CCP-2 and anti-CCP-3 antibodies assays.
1/2017	Female hormonal factors and the development of anti-citrullinated protein antibodies in women at risk of rheumatoid arthritis.
1/2017	Anti-Citrullinated Protein Antibodies Are Associated With Neutrophil Extracellular Traps in the Sputum in Relatives of Rheumatoid Arthritis Patients.
2/2015	Anti-CarP antibodies as promising marker to measure joint damage and disease activity in patients with rheumatoid arthritis.

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Michael Mahler Research Topics

Disease

31	Rheumatoid Arthritis 01/2023 - 11/2012
25	Rheumatic Diseases (Rheumatism) 01/2023 - 01/2007
21	Systemic Scleroderma (Systemic Sclerosis) 03/2023 - 08/2007
17	Systemic Lupus Erythematosus (Libman-Sacks Disease) 06/2022 - 12/2003
16	Autoimmune Diseases (Autoimmune Disease) 08/2022 - 01/2007
14	Myositis (Idiopathic Inflammatory Myopathies) 09/2023 - 01/2014
14	Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome) 01/2021 - 12/2012
8	Neoplasms (Cancer) 03/2023 - 02/2011
8	Thrombosis (Thrombus) 01/2023 - 12/2012
8	Inflammation (Inflammations) 01/2021 - 08/2016
7	Muscular Diseases (Myopathy) 11/2021 - 01/2014
6	Arthritis (Polyarthritis) 04/2024 - 01/2009
6	Interstitial Lung Diseases (Interstitial Lung Disease) 12/2021 - 03/2012
5	Polymyositis 02/2023 - 01/2005
5	COVID-19 12/2022 - 01/2020
4	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 12/2023 - 08/2013
4	Lung Diseases (Lung Disease) 12/2021 - 01/2020
4	Lupus Nephritis 02/2021 - 01/2013
4	Ulcerative Colitis 11/2017 - 08/2013
3	Connective Tissue Diseases (Connective Tissue Disease) 06/2022 - 08/2007
3	Prostatic Neoplasms (Prostate Cancer) 10/2021 - 12/2015
3	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 10/2020 - 01/2019
3	Venous Thrombosis (Deep-Vein Thrombosis) 12/2019 - 01/2017
3	Spontaneous Abortion (Miscarriage) 12/2019 - 01/2017
3	Dermatomyositis (Dermatopolymyositis) 12/2017 - 08/2007
2	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 12/2023 - 01/2014
2	Celiac Disease (Celiac Sprue) 12/2023 - 01/2014
2	Synovitis 01/2022 - 11/2020
2	Liver Diseases (Liver Disease) 01/2021 - 01/2020
2	Sclerosing Cholangitis 01/2021 - 01/2014
2	Atherosclerosis 12/2019 - 01/2017
2	Nephritis 01/2018 - 01/2013
2	Acquired Immunodeficiency Syndrome (AIDS) 12/2017 - 08/2016
2	Arthralgia (Joint Pain) 03/2017 - 03/2014
2	Asthma (Bronchial Asthma) 08/2016 - 11/2012
2	Calcinosis 06/2014 - 02/2011
2	Membranous Glomerulonephritis (Membranous Nephropathy) 01/2014 - 01/2013
2	Vasculitis (Vasculitides) 01/2014 - 10/2013
2	Granulomatosis with Polyangiitis (Wegener's Granulomatosis) 10/2013 - 08/2013
2	Crohn Disease (Crohn's Disease) 09/2013 - 08/2013
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 03/2023
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2023
1	Sjogren's Syndrome (Sjogren Syndrome) 06/2022
1	Confusion (Bewilderment) 06/2022
1	Pulmonary Arterial Hypertension 12/2021
1	Juvenile Arthritis (Juvenile Idiopathic Arthritis) 09/2021

Drug/Important Bio-Agent (IBA)

86	AntibodiesIBA 04/2024 - 12/2003
56	AutoantibodiesIBA 09/2023 - 01/2006
31	Biomarkers (Surrogate Marker)IBA 12/2023 - 01/2007
17	Proteins (Proteins, Gene)FDA Link 07/2022 - 01/2003
16	Antinuclear AntibodiesIBA 01/2023 - 01/2012
12	Immunoglobulin G (IgG)IBA 09/2022 - 05/2015
9	Peptides (Polypeptides)IBA 04/2024 - 01/2005
9	Anti-Citrullinated Protein AntibodiesIBA 04/2024 - 02/2015
9	AntigensIBA 01/2020 - 01/2007
8	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 12/2023 - 08/2013
8	Leukocyte L1 Antigen Complex (Calgranulin)IBA 12/2022 - 12/2019
8	Glycoproteins (Glycoprotein)IBA 01/2021 - 12/2012
8	EpitopesIBA 07/2020 - 01/2003
8	AutoantigensIBA 03/2018 - 12/2003
6	Immunoglobulin A (IgA)IBA 12/2023 - 03/2017
6	Phospholipids (Phosphatides)FDA LinkGeneric 01/2021 - 01/2017
6	EnzymesIBA 10/2019 - 01/2014
5	Rheumatoid FactorIBA 10/2021 - 12/2012
5	Antiphospholipid AntibodiesIBA 12/2020 - 05/2015
4	PhosphatidylserinesIBA 01/2023 - 05/2018
4	Prothrombin (Factor II)IBA 01/2023 - 05/2018
4	Type I DNA Topoisomerases (Topoisomerase I)IBA 01/2021 - 01/2007
4	Oxidoreductases (Dehydrogenase)IBA 01/2019 - 09/2015
4	ImmunosorbentsIBA 01/2019 - 01/2016
3	Myeloblastin (Proteinase 3)IBA 12/2023 - 08/2013
3	Protein-Arginine Deiminase Type 4IBA 09/2022 - 12/2012
3	trioctyl phosphine oxide (TOPO)IBA 12/2021 - 01/2007
3	lens epithelium-derived growth factorIBA 10/2021 - 11/2012
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 10/2016 - 01/2014
3	anticentromere antibodyIBA 04/2012 - 01/2010
2	Protein-Arginine DeiminasesIBA 01/2023 - 10/2019
2	Immunoglobulin M (IgM)IBA 10/2021 - 01/2019
2	RNA (Ribonucleic Acid)IBA 01/2021 - 01/2003
2	bioplexIBA 11/2020 - 01/2015
2	cyclic citrullinated peptideIBA 11/2020 - 03/2017
2	Lupus Coagulation Inhibitor (Lupus Anticoagulant)IBA 10/2020 - 01/2019
2	Carrier Proteins (Binding Protein)IBA 12/2019 - 01/2017
2	CytokinesIBA 12/2019 - 01/2017
2	Ligases (Synthetase)IBA 07/2019 - 04/2014
2	Signal Recognition ParticleIBA 01/2019 - 09/2015
2	TrypsinIBA 01/2019 - 06/2017
2	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 01/2017
2	Heat-Shock Proteins (Heat-Shock Protein)IBA 12/2017 - 08/2016
2	Phospholipase A2 ReceptorsIBA 01/2014 - 01/2013
2	Proliferating Cell Nuclear Antigen (PCNA)IBA 08/2012 - 01/2007
1	Protein Glutamine gamma Glutamyltransferase 2IBA 12/2023
1	HLA-DRB1 Chains (HLA DRB1)IBA 01/2023
1	Oxygen (Dioxygen)IBA 12/2021
1	IntegrasesIBA 10/2021
1	Docetaxel (Taxotere)FDA Link 10/2021

Therapy/Procedure

3	Precision Medicine 09/2022 - 10/2019
3	Therapeutics 12/2021 - 01/2009
1	Lung Transplantation 12/2021
1	Drug Therapy (Chemotherapy) 10/2021